@article{Oloyede2026,

title = {Chemical constituents and biological activities of essential oils of leaves and stem of Homalium africanum (Hook. F) Benth (Flacourtiaceae) and Shorea roxburghii G. Don (Dipterocarpaceae)},

author = {Ganiyat K. Oloyede and Patricia A. Onocha and Mokanjuola A. Olatunji and Michael G. Ibok and Abdul-Qowiy A. Fashola and Mariam A. Adepoju and Caleb O. Ojo and Oluwafemi O. Olalusi},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-6.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {Homalium africanum (Hook. F) Benth (Flacourtiaceae) and Shorea roxburghii G.Don (Dipterocarpaceae) are used in the treatment of malaria, cholera, degenerative and inflammatory diseases. This study was carried out to evaluate the chemical constituents, antioxidant, antimicrobial activities and cytotoxicity of the essential oils (EOs) of leaves and stems of both plants. H. africanum (HA) and S. roxburghii (SR) were collected and authenticated at Forestry Research Institute of Nigeria. The EOs were extracted by hydro-distillation. The chemical composition, antioxidant, antimicrobial activities and cytotoxicity of the EOs were carried out using Gas Chromatography-Mass Spectrometry (GC-MS), 2, 2-diphenyl-1-phenylhydrazyl radical (DPPH), broth dilution method and brine shrimp lethality assays, respectively. Also, the minimum inhibition concentration (MIC) and minimum microbicidal concentration (MMC) were determined. GC-MS analyses of the EOs from H. africanum gave twenty-six compounds for the leaf (76.64%) and sixteen compounds for the stem (35.77%). Leaf and stem EOs were dominated with 2-hexanol (6.06%) and benzaldehyde (43.43%), respectively. S. roxburghii EOs revealed a total of forty-two compounds for leaf (73.99%) and fourteen compounds for the stem (76.64%). Leaf EO was dominated with caryophyllene oxide (8.85%) and 1H-cyclopropazulen-7-ol (8.62%) and stem EO with α- and β- phellandrene (36.02%) and limonene (26.16%). The EOs of leaves and stem of both plants showed moderate antioxidant activity with IC50 (mg/ml) of 1.51, 2.64 (HA) and 1.50, 1.73 (SR), respectively; moderate inhibitory (MIC μg/ml: 0.39-50) and microbicidal activity (MMC μg/ml: 0.39-25-HA, 1.56-50-SR) against all microbes used except Pseudomonas aeruginosa, Klebsiella pneumoniae and Apergillus niger. The EOs of leaves and stem of both plants were cytotoxic, with LC50 (μg/ml) of 5.1470, 3.465 (HA) and 4.69, 5.767 (SR), respectively. The results corroborate the plants’ ethno-medicinal uses.},

keywords = {2, 2-diphenyl-1-picryhydrazyl, brine shrimp lethality assay, Essential oils, Homalium africanum, radical assay, Shorea roxburghii},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Chemical profiling and DPPH radical scavenging activity of fruit essential oil of Eucalyptus camaldulensis Dehnh. native to north-central, Nigeria},

author = {Ridwan Olanrewaju Ismaeel and Lamidi Ajao Usman and Gabriel Taiwo Oyelowo and Oyeleye Medinat Adedeji and Ibrahim Murtala Muhammad and Terlumun Samuel Tosabo},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-5.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {This study investigated the chemical constituents and antioxidant activity of the volatile oil from the fruit of Eucalyptus camaldulensis. Pulverized fruits (500 g) of the plant afforded 0.58% (w/w) of essential oil after hydro-distillation. The chemical profile of the oil was characterized by GC-MS, which revealed twenty-one (21) compounds accounting for 99.4% of the total composition. The principal components of the oil included: β-ocimene, α-pinene, β-pinene, 2-carene, limonene, and β-caryophyllene. The essential oil scavenged DPPH radical with an IC50 value of 9.86±0.02 μL/mL, showing activity comparable to that of ascorbic acid, which was used as a reference compound. Therefore, the oil may serve as a natural antioxidant for oxidative stress management and its complications, pending clinical validation.},

keywords = {DPPH radical, Eucalyptus camaldulensis, Fruit volatile oil, α- pinene, β-ocimene},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Chemical composition, antimicrobial and antioxidant activities of leaf and twig essential oils of Micriodesmis puberula (Pandaceae)},

author = {Patricia A. Onocha and Ganiyat K. Oloyede and Marvellous E. Erakhumen and Michael G. Ibok and Samuel Onuche and Oluwatoyosi M. Ikotun and Olarewaju L. Idriz},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-4.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {Microdesmis puberula (PROTA) is widely utilised in traditional medicine across West and Central Africa for treating infections, inflammatory conditions, and reproductive disorders. This study presents the first comparative chemical and bioactivity analysis of essential oils derived from the leaves and twigs of this plant. Essential oils were extracted via hydrodistillation and characterised using GC-MS. Antimicrobial properties were assessed against six bacterial and four fungal strains using agar diffusion assays, while antioxidant activity was evaluated through DPPH free radical scavenging. The leaf and twig oils yielded 0.16% and 0.18% (w/w), respectively, and comprised 21 and 11 identified compounds, respectively. Leaf oil was dominated by non-terpenoids (43.27%), with (3E,7E)-4,8,12-trimethyltridec-1,3,7,11-tetraene as the major constituent, whereas twig oil contained high levels of fatty acids, predominantly palmitic acid (44.72%). Both oils exhibited moderate, concentration-dependent antimicrobial activity, with the twig oil showing notable inhibition against Pseudomonas aeruginosa (18±0.003 - 10±0.000 mm) and Salmonella typhi (18±0.003 - 10±0.002 mm). Antioxidant evaluation revealed moderate radical-scavenging capacity, with IC₅₀ values of 1.00 μg/mL (leaf) and 1.35 μg/mL (twig). The bioactivity of the oils may be attributed to synergistic interactions among major and minor constituents. These findings support the ethnopharmacological relevance of M. puberula and highlight its potential as a natural antimicrobial and antioxidant agent.},

keywords = {Antimicrobial activity, Antioxidant activity, Chemical constituents, Essential oils, Hydrodistillation, Microdesmis puberula},

pubstate = {published},

tppubtype = {article}

}

@article{Idowu2026,

title = {GC-MS Profile and toxicity study of essential oil, hydrosol and crude extracts of Nerium oleander L. Leaves},

author = {Mary O. Idowu and Sherifat A. Aboaba},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-3.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {Nerium oleander L. also known as oleander, belongs to the Apocynaceae family. It is an evergreen ornamental shrub that grows in tropical, subtropical, and Mediterranean climates. Essential oil and hydrosol were obtained from the plant material by hydro-distillation, methanol extract by solvent extraction which was fractionated with n-hexane and ethyl acetate. Gas chromatography-mass spectrophotometry (GC-MS) was employed for analyses of the extracts, and Brine Shrimp Lethality Assay for the toxicity study. The GC-MS analyses of the essential oil, hydrosol, n-hexane, ethyl acetate and methanol extracts afforded 38, 32, 27, 31, and 37 compounds, respectively, representing 99.99, 99.98, 99.99, 100, and 100 % of the total constituents respectively. The profile of the constituents can be described as terpene, fatty acid, amide, phenolic and aromatic compounds, respectively. Major components were (+)-intermedeol (18.63 %), 1-chloroheptacosane (23.76 %), squalene (15.02 %), 2-O-methyl-d-xylose (14.04 %), 2-O-methyl-d-xylose (48.77 %) respectively. The brine shrimps lethality assay yielded LC50 values of 317332.39, 0.00, 0.00, 1532.00 and 185587578.80 ppm, respectively. The LC50 values reveal that essential oil, ethyl acetate and methanol extracts were non-toxic, indicating their safety for biological applications in pharmaceuticals, cosmetics, and food products, while hydrosol and n-hexane extract demonstrated significant toxicity, suggesting promising bioactive potential. These findings highlight the variability in the oil composition and toxicity profiles of N. oleander leaf extracts obtained using different solvents and identify the potential of the extracts for exploration in the treatment of diseases.},

keywords = {Artemia salina, GC-MS, Nerium oleander, Toxicity},

pubstate = {published},

tppubtype = {article}

}

@article{Imade2026b,

title = {HPLC analysis and subacute effect of Senna alata (L.) root and Xylopia aethiopica (Dunal) A. Rich seed on steroidal hormones associated with fibroid},

author = {Rose Osarieme Imade and Toluwalase Adu-Fatoba},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-2-1.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {Uterine fibroids, influenced by estrogen and progesterone, are common benign tumors in women of reproductive age. This work researched the action of Senna alata root and Xylopia aethiopica seed on progesterone and estradiol levels in female Wistar rats. Animal studies were conducted by administering 100 and 200 mg/kg doses of each extract to test animals daily for 28 consecutive days, after which blood samples were collected. Serum was analyzed for estradiol and progesterone levels using standard biochemical assays. High-Performance Liquid Chromatography (HPLC) was employed to identify the phytoconstituents in the ethanol extracts of the plants. S. alata significantly reduced progesterone levels (p<0.001) at both concentrations, while X. aethiopica showed marked activity only at 200 mg/kg (p<0.01). Estradiol levels remained unchanged with both extracts. HPLC identified bioactive compounds like kaempferol, trans-resveratrol and adenine in S. alata roots, and beta-phellandrene, kaempferol and umbelliferone in X. aethiopica seeds. These findings suggest hormone regulatory effects of these plants, warranting further research into their efficacy and mechanisms for fibroid management.},

keywords = {Estradiol, Fibroid, HPLC, Progesterone, Senna alata, Xylopia aethiopica},

pubstate = {published},

tppubtype = {article}

}

@article{Imade2026,

title = {Subacute effect of Momordica charantia plant, Tetrapleura tetraptera fruit and Allium cepa bulb on steroidal hormones},

author = {Rose Osarieme Imade and Temitope Jemimah Alakija},

url = {https://journal.seoda.org/wp-content/uploads/2026/03/ARTICLE-1-1.pdf},

year  = {2026},

date = {2026-02-15},

urldate = {2026-02-15},

journal = {SEODA Journal of Aromatic and Medicinal Plants },

volume = {1},

abstract = {Fibroids are hormone-dependent tumors influenced by elevated levels of estradiol and progesterone. The search for natural alternatives to conventional treatments has led to the investigation of plant-based therapies. This study evaluates the phytochemical composition and effect of Momordica charantia L. (Cucurbitaceae) plant, Tetrapleura tetraptera (Schum. & Thonn.) Taub. (Mimosaceae) fruit and Allium cepa L. (Amaryllidaceae) bulb on serum cholesterol, estradiol, and progesterone implicated in fibroid growth. Animal studies were conducted by administering 100 and 200 mg/kg doses of each plant extract to Wistar rats over 28 days, after which blood samples were collected. Serum was analyzed for changes in cholesterol, estradiol, and progesterone levels using standard biochemical assays. High-Performance Liquid Chromatography was employed to identify the phytoconstituents in the ethanol extracts of the plants. The results showed that A. cepa significantly lowered serum cholesterol levels (p < 0.05), while M. charantia and T. tetraptera did not produce statistically significant reductions. None of the plant extracts caused a significant decrease in estradiol levels, however, A. cepa and T. tetraptera significantly reduced serum progesterone levels, suggesting potential anti-fibroid activity. Phytochemical analysis confirmed the presence of bioactive compounds that may contribute to these effects. These findings suggest that the tested plant extracts, particularly A. cepa and T. tetraptera, may have potential in managing fibroid growth through hor},

keywords = {Allium cepa, Fibroid, HPLC, Momordica charantia, Steroidal hormones, Tetrapleura tetraptera},

pubstate = {published},

tppubtype = {article}

}